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Human's interaction with Antarctica are "harvesting some Antarctic species to the verge of extinction for economic benefit, killing and disturbing other species, contaminating the soils, and discharging sewage to the sea and leaving rubbish, cairns and tracks in even the most remote parts."

 

This can affect the flora and fauna in the area, there are also concerns about people fishing in Antarctica like "potential for over-fishing of target species, effects on predator populations dependant on the target species as a food source, mortality of non-target species caught by fishing equipment and destruction of habitat."

 

Taken from the department of arctic division. http://www.antarctica.gov.au/environment/human-impacts-in-antarctica

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